It has been proven scientifically and observed generally that about 100% of people in the age group of ten to eighteen have at least some bouts of acne, in the form of comedones (blackheads or whiteheads) or pimples or in some cases, and mostly boys, nodules. It does not depend which race or ethnicity one comes from, acne can be called a universal phenomena in adolescent human beings. It is most rampant in that age group because of changes in the hormones. This hormonal imbalance or general change due to reproductive maturity causes those ugly lesions. Hormone levels are generally high and active. Thus this excites the oil or sebaceous glands, which then, along with the sebum, dead skin cells and tiny hairlets forms an acne lesion.

Ten to thirteen years is the most commonly observed age group where acne starts appearing. It lasts up to a maximum of ten years, which is marked by ne peak year which is the most affected stage. Nodular or cystic acne appear at this time. This may take a while to heal, unlike the other less severe forms. Teenagers become insecure and short-tempered due to the facial unpleasantness mainly. Sometimes these adolescent acne can continue up to adulthood also.